What motherboard suits Ryzen Threadripper PRO 3995WX, and how should power delivery, memory, and ports be balanced?

  The 3995WX only fits sWRX8 boards with the WRX80 chipset — a handful of flagship workstation models from ASUS, Gigabyte, and MSI, all expensive and mostly bought new or through business channels.

  Memory is eight-channel DDR4 ECC RDIMM; populate it per the manual or you lose bandwidth. Expansion is the platform's strength — tons of PCIe lanes for GPUs, compute cards, NVMe, and NICs — but bifurcation settings live in the BIOS and the manual really matters. This is not a gamer's platform; the parts around the CPU cost more than the CPU.